Search on: RIBOSOMAL PROTEIN S6 KINASES, 70-KDA 
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Descriptor English:   Ribosomal Protein S6 Kinases, 70-kDa 
Descriptor Spanish:   Proteínas Quinasas S6 Ribosómicas 70-kDa 
Descriptor Portuguese:   Proteínas Quinases S6 Ribossômicas 70-kDa 
Synonyms English:   p70 S6 Kinase
p70s6k  
Tree Number:   D08.811.913.696.620.682.700.862.249
D12.644.360.600.249
D12.776.476.600.249
Definition English:   A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed. 
History Note English:   2005(2003); for P70 S6 KINASE & P70S6K use RIBOSOMAL PROTEIN S6 KINASES 1998-2002 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   37341 
Unique Identifier:   D038762 

Occurrence in VHL:
 

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